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1

Nucleoside Analogs with Selective Antiviral Activity Against Dengue Fever and Japanese Encephalitis Viruses

Zandi, Keivan, Bassit, Leda, Amblard, Franck, Cox, Bryan D., Hassandarvish, Pouya, Moghaddam, Ehsan, Yueh, Andrew, Libanio Rodrigues, Gisele Olinto, Passos, Ingredy, Costa, Vivian V., AbuBakar, Sazaly

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2019

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2019

2

Spontaneous hepatitis B surface antigen clearance in a long-term follow-up study of patients with chronic type B hepatitis. Lack of correlation with hepatitis C and D virus superinfection

Luiz Caetano Da Silva, Carmen Lúcia De Assis Madruga, Flair José Carrilho, João Renato Rebello Pinho, Amadeo Saéz-Alquezar, Carlos Santos, Leda Bassit, Claudia Barreto, Luís Edmundo Pinto Da Fonseca,

Journal:

Journal of Gastroenterology

Année:

1996

Langue:

english

Fichier:

PDF, 630 KB

english, 1996

3

Towards HBV curative therapies

Schinazi, Raymond F., Ehteshami, Maryam, Bassit, Leda, Asselah, Tarik

Journal:

Liver International

Année:

2018

Langue:

english

Fichier:

PDF, 1003 KB

english, 2018

4

Encephalopathy and Encephalitis Associated with Cerebrospinal Fluid Cytokine Alterations and Coronavirus Disease, Atlanta, Georgia, USA, 2020

Benameur, Karima, Agarwal, Ankita, Auld, Sara C., Butters, Matthew P., Webster, Andrew S., Ozturk, Tugba, Howell, J. Christina, Bassit, Leda C., Velasquez, Alvaro, Schinazi, Raymond F., Mullins, Mark

Journal:

Emerging Infectious Diseases

Année:

2020

Fichier:

PDF, 1.08 MB

2020

5

Genotype distribution of hepatitis C virus in São Paulo, Brazil: Rare subtype found

Leda Bassit, Gabriela Ribeiro-Dos-Santos, Luiz C. Da Silva, Kioko Takei, Paula Villaça, Elias David-Neto, Dalton Chamone, Amadeo Sáez-Alquézar

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 34 KB

english, 1999

6

Hepatitis G Virus: Prevalence and Sequence Analysis in Blood Donors of São Paulo, Brazil

Leda Bassit, Bernhard Kleter, Gabriela Riberiro-dos-Santos, Geert Maertens, Ester Sabino, Dalton Chamone, Wim Quint, Amadeo Sáez-Alquézar

Journal:

Année:

1998

Fichier:

PDF, 735 KB

1998

7

High rate of sustained response to consensus interferon plus ribavirin in chronic hepatitis C patients resistant to alpha-interferon and ribavirin: a pilot study

Luiz Caetano da Silva, Leda Bassit, Suzane Kioko Ono-Nita, João Renato Rebello Pinho, Ana Nishiya, Carmen Lucia Madruga, Flair José Carrilho

Journal:

Journal of Gastroenterology

Année:

2002

Langue:

english

Fichier:

PDF, 60 KB

english, 2002

8

Long-Term Exposure to AZT, but not d4T, Increases Endothelial Cell Oxidative Stress and Mitochondrial Dysfunction

Erik R. Kline, Leda Bassit, Brenda I. Hernandez-Santiago, Mervi A. Detorio, Bill Liang, Dean J. Kleinhenz, Erik R. Walp, Sergey Dikalov, Dean P. Jones, Raymond F. Schinazi, Roy L. Sutliff

Journal:

Cardiovascular Toxicology

Année:

2009

Langue:

english

Fichier:

PDF, 481 KB

english, 2009

9

Synthesis and antiviral activity of 2′-deoxy-2′-fluoro-2′-C-methyl-7-deazapurine nucleosides, their phosphoramidate prodrugs and 5′-triphosphates

Junxing Shi, Longhu Zhou, Hongwang Zhang, Tamara R. McBrayer, Mervi A. Detorio, Melissa Johns, Leda Bassit, Megan H. Powdrill, Tony Whitaker, Steven J. Coats, Matthias Götte, Raymond F. Schinazi

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 297 KB

english, 2011

10

Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3′-azido-2′,3′-dideoxypurine nucleosides

Hong-wang Zhang, Mervi Detorio, Brian D. Herman, Sarah Solomon, Leda Bassit, James H. Nettles, Aleksandr Obikhod, Si-jia Tao, John W. Mellors, Nicolas Sluis-Cremer, Steven J. Coats, Raymond F. Schinaz

Journal:

European Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 962 KB

english, 2011

11

Hepatitis B virus infection in Haemodialysis Centres from Santa Catarina State, Southern Brazil. Predictive risk factors for infection and molecular epidemiology

Flair J Carrilho, Cleusa R Moraes, João RR Pinho, Isabel MVGC Mello, Dennis A Bertolini, Marcílio F Lemos, Regina C Moreira, Leda C Bassit, Rita A Cardoso, Gabriela Ribeiro-dos-Santos, Luiz C Da Silva

Journal:

BMC Public Health

Année:

2004

Langue:

english

Fichier:

PDF, 302 KB

english, 2004

12

A prospective study of the prevalence of hepatitis B and C virus co-infection among patients with chronic renal disease under hemodialysis

Suzane K Ono-Nita, Cleusa R de Moraes, Flair J Carrilho, João R.R Pinho, Leda Bassit, Luiz C da Silva

Journal:

Journal of Hepatology

Année:

2004

Langue:

english

Fichier:

PDF, 79 KB

english, 2004

13

Phylogenetic classification of TT virus groups based on the N22 region is unreliable

Philippe Lemey, Marco Salemi, Leda Bassit, Anne-Mieke Vandamme

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 331 KB

english, 2002

14

Adenosine Dioxolane Nucleoside Phosphoramidates As Antiviral Agents for Human Immunodeficiency and Hepatitis B Viruses

Bondada, Lavanya, Detorio, Mervi, Bassit, Leda, Tao, Sijia, Montero, Catherine M., Singletary, Tyana M., Zhang, Hongwang, Zhou, Longhu, Cho, Jong-Hyun, Coats, Steven J., Schinazi, Raymond F.

Journal:

ACS Medicinal Chemistry Letters

Année:

2013

Langue:

english

Fichier:

PDF, 534 KB

english, 2013

15

Synthesis and Anti-Hepatitis B Virus and Anti-Hepatitis C Virus Activities of 7-Deazaneplanocin A Analogues in Vitro

Kim, Hyo-Joong, Sharon, Ashoke, Bal, Chandralata, Wang, Jianing, Allu, Madhan, Huang, Zhuhui, Murray, Michael G., Bassit, Leda, Schinazi, Raymond F., Korba, Brent, Chu, Chung K.

Journal:

Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 156 KB

english, 2009

16

Hepatitis C virus genotyping by means of 5′-UR/core line probe assays and molecular analysis of untypeable samples

Stuyver, Lieven, Wyseur, Ann, van Arnhem, Wouter, Lunel, Françoise, Laurent-Puig, Pierre, Pawlotsky, Jean-Michel, Kleter, Bernhard, Bassit, Leda, Nkengasong, John, van Doorn, Leen-Jan

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1995

17

Synthesis and antiviral evaluation of 2-amino-6-carbamoylpurine dioxolane nucleoside derivatives and their phosphoramidates prodrugs

Cho, Jong Hyun, Bondana, Lavanya, Detorio, Mervi A., Montero, Cathy, Bassit, Leda C., Amblard, Franck, Coats, Steven J., Schinazi, Raymond F.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 692 KB

english, 2014

18

Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease

Kennedy, Edward M., Bassit, Leda C., Mueller, Henrik, Kornepati, Anand V.R., Bogerd, Hal P., Nie, Ting, Chatterjee, Payel, Javanbakht, Hassan, Schinazi, Raymond F., Cullen, Bryan R.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.76 MB

english, 2015

19

β- d -2′- C -Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted Intracellularly to Bioactive 2,6-Diaminopurine and Guanosine 5′-Triphosphate Forms

Zhou, Longhu, Zhang, Hong-wang, Tao, Sijia, Bassit, Leda, Whitaker, Tony, McBrayer, Tamara R., Ehteshami, Maryam, Amiralaei, Sheida, Pradere, Ugo, Cho, Jong Hyun, Amblard, Franck, Bobeck, Drew, Detori

Journal:

Journal of Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.11 MB

english, 2015

20

Characterization of dengue virus 2 growth in megakaryocyte–erythrocyte progenitor cells

Clark, Kristina B., Hsiao, Hui-Mien, Bassit, Leda, Crowe, James E., Schinazi, Raymond F., Perng, Guey Chuen, Villinger, Francois

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.28 MB

english, 2016

21

Toward Elimination of Hepatitis B Virus Using Novel Drugs, Approaches, and Combined Modalities

Boucle, Sebastien, Bassit, Leda, Ehteshami, Maryam, Schinazi, Raymond F.

Journal:

Clinics in Liver Disease

Année:

2016

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2016

22

Synthesis and antiviral evaluation of fluorinated acyclo-nucleosides and their phosphoramidates

Mahmoud, Sawsan, Li, Hao, McBrayer, Tamara R., Bassit, Leda, Hammad, Sherif F., Coats, Steven J., Amblard, Franck, Schinazi, Raymond F.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Année:

2016

Langue:

english

Fichier:

PDF, 893 KB

english, 2016

23

Approaches to hepatitis C treatment and cure using NS5A inhibitors

Schinazi, Raymond, Kohler, James, Nettles, James, Amblard, Franck, Hurwitz, Selwyn, Bassit, Leda, Stanton, Richard, Ehteshami, Maryam

Journal:

Infection and Drug Resistance

Année:

2014

Langue:

english

Fichier:

PDF, 2.38 MB

english, 2014

24

Synthesis and antiviral evaluation of novel heteroarylpyrimidines analogs as HBV capsid effectors

Boucle, Sebastien, Lu, Xiao, Bassit, Leda, Ozturk, Tugba, Russell, Olivia Ollinger, Amblard, Franck, Coats, Steven J., Schinazi, Raymond F.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2017

Langue:

english

Fichier:

PDF, 890 KB

english, 2017

25

Synthesis and antiviral evaluation of 2′,2′,3′,3′-tetrafluoro nucleoside analogs

Sari, Ozkan, Bassit, Leda, Gavegnano, Christina, McBrayer, Tamara R., McCormick, Louise, Cox, Bryan, Coats, Steven J., Amblard, Franck, Schinazi, Raymond F.

Journal:

Tetrahedron Letters

Année:

2017

Langue:

english

Fichier:

PDF, 874 KB

english, 2017

26

Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network

Aliota, Matthew T., Bassit, Leda, Bradrick, Shelton S., Cox, Bryan, Garcia-Blanco, Mariano A., Gavegnano, Christina, Friedrich, Thomas C., Golos, Thaddeus G., Griffin, Diane E., Haddow, Andrew, Kallas

Journal:

Antiviral Research

Année:

2017

Langue:

english

Fichier:

PDF, 2.18 MB

english, 2017

27

2’-Chloro,2’-Fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture

Zhou, Shaoman, Mahmoud, Sawsan, Liu, Peng, Zhou, Longhu, Ehteshami, Maryam, Bassit, Leda, Tao, Sijia, Domaoal, Robert A., Sari, Ozkan, De Schutter, Coralie, Amiralaei, Sheida, Khalil, Ahmed, Ollinger

Journal:

Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 785 KB

english, 2017

28

Synthesis of sulfamoylbenzamide derivatives as HBV capsid assembly effector

Sari, Ozkan, Boucle, Sebastien, Cox, Bryan D., Ozturk, Tugba, Russell, Olivia Ollinger, Bassit, Leda, Amblard, Franck, Schinazi, Raymond F.

Journal:

European Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2017

29

Acute acalculous cholecystitis during zika virus infection in an immunocompromised patient

Ono, Suzane Kioko, Bassit, Leda, Van Vaisberg, Victor, Avancini Ferreira Alves, Venâncio, Caldini, Elia G., Herman, Brian D., Shabman, Reed, Fedorova, Nadia B., Paranaguá-Vezozzo, Denise, Sampaio, Car

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 387 KB

english, 2018

30

Genotype distribution of the GB virus C in citizens of São Paulo City, Brazil

Nishiya, Anna S., Ribeiro-Dos-Santos, Gabriela, Bassit, Leda, Focaccia, Roberto, Chamone, Dalton F., Sabino, Ester C.

Journal:

Revista do Instituto de Medicina Tropical de São Paulo

Année:

2003

Langue:

english

Fichier:

PDF, 213 KB

english, 2003

31

New prevalence estimate of TT virus (TTV) infection in low- and high-risk population from São Paulo, Brazil

BASSIT, Leda, TAKEI, Kioko, HOSHINO-SHIMIZU, Sumie, NISHIYA, Anna S., SABINO, Ester C., BASSITT, Rogério P., FOCACCIA, Roberto, D'AMICO, Élbio, CHAMONE, Dalton F., RIBEIRO-DOS-SANTOS, Gabriela

Journal:

Revista do Instituto de Medicina Tropical de São Paulo

Année:

2002

Langue:

english

Fichier:

PDF, 40 KB

english, 2002

32

Synthesis and anti-HCV activity of β-d-2′-deoxy-2′-α-chloro-2′-β-fluoro and β-d-2′-deoxy-2′-α-bromo-2′-β-fluoro nucleosides and their phosphoramidate prodrugs

Ovadia, Reuben, Khalil, Ahmed, Li, Hao, De Schutter, Coralie, Mengshetti, Seema, Zhou, Shaoman, Bassit, Leda, Coats, Steven J., Amblard, Franck, Schinazi, Raymond F.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 846 KB

english, 2019

33

Discovery of a Series of 2’-α-Fluoro,2’-β-Bromo-Ribonucleosides and their Phosphoramidate Prodrugs as Potent Pan-Genotypic Inhibitors of Hepatitis C Virus

MENGSHETTI (BAGMARE), SEEMA, Zhou, Longhu, Sari, Ozkan, De Schutter, Coralie, Zhang, Hongwang, Cho, Jong Hyun, Tao, Sijia, Bassit, Leda, Verma, Kiran, Domaoal, Robert, Ehteshami, Maryam, Jiang, Yong,

Journal:

Journal of Medicinal Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2019

34

Nucleoside Analogs with Antiviral Activity Against Yellow Fever Virus

Zandi, Keivan, Amblard, Franck, Amichai, Sarah, Bassit, Leda, Tao, Sijia, Jiang, Yong, Zhou, Longhu, Russell, Olivia Ollinger, Mengshetti, Seema, Schinazi, Raymond F.

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2019

Langue:

english

Fichier:

PDF, 990 KB

english, 2019

35

Nucleoside Analogs with Antiviral Activity Against Yellow Fever Virus

Zandi, Keivan, Amblard, Franck, Amichai, Sarah, Bassit, Leda, Tao, Sijia, Jiang, Yong, Zhou, Longhu, Russell, Olivia Ollinger, Mengshetti, Seema, Schinazi, Raymond F.

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2019

Fichier:

PDF, 990 KB

2019

36

Synthesis of 7-trifluoromethyl-7-deazapurine ribonucleoside analogs and their monophosphate prodrugs

Cho, Jong Hyun, Bassit, Leda C., Amblard, Franck, Schinazi, Raymond F.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Année:

2019

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2019

37

FRI-157-Novel HBV capsid assembly modulator inhibits pregenomic RNA encapsidation by accelerating capsid assembly kinetics and disrupting core protein dephosphorylation

Bassit, Leda, Verma, Kiran, Ono, Suzane Kioko, Cox, Bryan, amblard, franck, Schinazi, Raymond F

Journal:

Journal of Hepatology

Année:

2019

Langue:

english

Fichier:

PDF, 229 KB

english, 2019

38

Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses in Vitro and in Humanized Mice

Amblard, Franck, Boucle, Sebastien, Bassit, Leda, Cox, Bryan, Sari, Ozkan, Tao, Sijia, Chen, Zhe, Ozturk, Tugba, Verma, Kiran, Russell, Olivia, Rat, Virgile, de Rocquigny, Hugues, Fiquet, Oriane, Bous

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2019

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2019

39

Visualization of Positive and Negative Sense Viral RNA for Probing the Mechanism of Direct-Acting Antivirals against Hepatitis C Virus

Liu, Dandan, Tedbury, Philip R., Lan, Shuiyun, Huber, Andrew D., Puray-Chavez, Maritza N., Ji, Juan, Michailidis, Eleftherios, Saeed, Mohsan, Ndongwe, Tanyaradzwa P., Bassit, Leda C., Schinazi, Raymon

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 4.11 MB

english, 2019

40

Potent in vitro activity of β-D-4ʹ-chloromethyl-2ʹ-deoxy-2ʹ-fluorocytidine against Nipah virus

Lo, Michael K., Amblard, Franck, Flint, Mike, Chatterjee, Payel, Kasthuri, Mahesh, Li, Chengwei, Russell, Olivia, Verma, Kiran, Bassit, Leda, Schinazi, Raymond F., Nichol, Stuart T., Spiropoulou, Chri

Journal:

Antiviral Research

Année:

2020

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2020

41

Synthesis of 4â²-Substituted-2â²-Deoxy-2â²-Î±-Fluoro Nucleoside Analogs as Potential Antiviral Agents

Kasthuri, Mahesh, Li, Chengwei, Verma, Kiran, Russell, Olivia Ollinger, Dickson, Lyndsey, McCormick, Louise, Bassit, Leda, Amblard, Franck, Schinazi, Raymond F.

Journal:

Année:

2020

Langue:

english

Fichier:

PDF, 1.88 MB

english, 2020

42

Novel 1â²-homo- N -2â²-deoxy-Î±-nucleosides: synthesis, characterization and biological activity

Carnero, Alejandro, MartÃn-Nieves, Virginia, Sanghvi, Yogesh S., Russel, Olivia O., Bassit, Leda, Schinazi, Raymond F., FernÃ¡ndez, Susana, Ferrero, Miguel

Journal:

Année:

2020

Fichier:

PDF, 833 KB

2020

43

7-Deaza-7-Fluoro-2â-C-Methyladenosine Inhibits Zika virus Infection and Viral-induced Neuroinflammation

Del Sarto, Juliana Lemos, de Paiva Froes Rocha, Rebeca, Bassit, Leda, Olmo, Isabella GuimarÃ£es, Valiate, Bruno, Queiroz-Junior, Celso M., da Silva Gouveia Pedrosa, Carolina, Ribeiro, FabÃola Mara, G

Journal:

Antiviral Research

Année:

2020

Fichier:

PDF, 2.79 MB

2020

44

Erratum for Amblard et al., âNovel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses In Vitro and in Humanized Miceâ

Amblard, Franck, Boucle, Sebastien, Bassit, Leda, Cox, Bryan, Sari, Ozkan, Tao, Sijia, Chen, Zhe, Ozturk, Tugba, Verma, Kiran, Russell, Olivia, Rat, Virgile, de Rocquigny, Hugues, Fiquet, Oriane, Bous

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2020

Fichier:

PDF, 155 KB

2020

45

Repurposing Nucleoside Analogs for Human Coronaviruses

Zandi, Keivan, Amblard, Franck, Musall, Katie, Downs-Bowen, Jessica, Kleinbard, Ruby, Oo, Adrian, Cao, Dongdong, Liang, Bo, Russell, Olivia O., McBrayer, Tamara, Bassit, Leda, Kim, Baek, Schinazi, Ray

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2020

Fichier:

PDF, 1.13 MB

2020

46

Antibody Profiles According to Mild or Severe SARS-CoV-2 Infection, Atlanta, Georgia, USA, 2020

Hu, William T., Howell, J. Christina, Ozturk, Tugba, Benameur, Karima, Bassit, Leda C., Ramonell, Richard, Cashman, Kevin S., Pirmohammed, Shama, Roback, John D., Marconi, Vincent C., Yang, Irene, Mac

Journal:

Emerging Infectious Diseases

Année:

2020

Fichier:

PDF, 1.05 MB

2020